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Name:
David Daniel Raphael Sebinger
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Nationality:
Austria |
Institute:
The Max Bergmann Centre of Biomaterials Dresden - Cluster of Excellence
Budapester Strasse 27
01069 Dresden, Germany
http://www.mbc-dresden.de
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Qualifications:
Master of Science equivalent, area of specialization: Genetics.
At the Vienna University of Life Sciences, Austria.
(In Austria: the academic degree of “ Magister rerum naturalium” in the field of genetics.)
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Work being undertaken on behalf of KIDSTEM:
Promoting the differentiation and organisation of different types of stem cells into functional nephrons by designing new synthetic scaffolds as part of the tissue engineering and biomaterials team:
Our aim is to produce a series of biomaterials with defined chemical modifications and topographies that will be screened for their ability to trigger ECM reorganisation and support nephrogenesis using cells harvested from embryonic mouse metanephroi and isolated metanephric mesenchyme.
Based on the most promising modified biomaterials/ECM mimics, we will then fabricate biomaterial scaffolds that will be screened for their ability to support nephrogenesis using KSCs, AFSCs, ESCs and MSCs.
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Previous Experience in:
Cancer Research (Correlation of Mutations of the gene encoding for FAS with Lymphoma frequency).
Epigenetics (X-Inactivation Pathway and RNAi).
Developmental Genetics (Specific Gen Expression and Proteins involved in the event of X chromosomal silencing).
Stem Cell Keeping (Culturing and Sub-culturing murine Embryonic Stem cells).
Structural Biology (Investigations of the Binding potential of DNA binding Proteins).
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Interests:
Scientific:
– Bio-(nano)-Technology
– Regenerative Medicine/Tissue Engineering
– Biomaterials
– Stem cells
– Structural Biology
– Medical/Industrial applications of molecular biological inventions
– (Epi-)Genetics
– Theoretical Biology
Personal:
Botany
Zoology
Physics/Astronomy
History
Philosophy
Politics
Economy
Electronic Equipment
Sports
Architectural Monuments
Antiques
Horror/Science-Fiction Literature/Motion Pictures
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References (please provide a link)
¯ Wohlfart S, Sebinger D, Gruber P, Buch J, Polgar D, Krupitza G, Rosner M, Hengstschlager M, Raderer M, Chott A, Mullauer L.
FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma.
Am J Pathol. 2004 Mar;164(3):1081-9.
PMID: 14982861
¯ Mullauer L, Gruber P, Sebinger D, Buch J, Wohlfart S, Chott A.
Mutations in apoptosis genes: a pathogenetic factor for human disease.
Mutat Res. 2001 Jul;488(3):211-31. Review.
PMID: 11397650
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